Safety Data Sheet
Dow Chemical Company Ltd

Dow Chemical Company Ltd

 encourages and expects you to read and understand the entire (M)SDS, as there is important information throughout the document.  We expect you to follow the precautions identified in this document unless your use conditions would necessitate other appropriate methods or actions.
1.	Identification of the substance/preparation and of the company/undertaking
Product Name
Propanol

Use of the substance/preparation 
Industrial solvent.  Chemical intermediate.  Dow recommends that you use this product in a manner consistent with the listed use. If your intended use is not consistent with Dow's stated use, please contact Dow's Customer Information Group.  

Company Identification
Dow Chemical Company Ltd
2 Heathrow Blvd., 284 Bath Rd
UB7 0DQ  West Drayton, Middlesex, EN
United Kingdom

Customer Information Number:	0208-917-5000
For questions about this SDS, contact: SDSQuestion@dow.com

Emergency Telephone Number24-Hour Emergency Contact:	+44 (0) 1553 761 251	Local Emergency Contact:00 44 155 37 61 251

2.	Hazards Identification

Highly flammable.
Risk of serious damage to eyes.
Vapours may cause drowsiness and dizziness.

3.	Composition/information on ingredients

Component	AmountClassification:CAS #	EC #
Propan-1-ol; n-propanol	100.0 %F: R11; Xi: R41; R67	71-23-8	200-746-9
	
See Section 16 for full text of R-phrases.
4.	First-aid measures

Eye Contact: Wash immediately and continuously with flowing water for at least 30 minutes.  Remove contact lenses after the first 5 minutes and continue washing. Obtain prompt medical consultation, preferably from an ophthalmologist.  
Skin Contact: Wash skin with plenty of water.  
Inhalation: Move person to fresh air.  If not breathing, give artificial respiration; if by mouth to mouth use rescuer protection (pocket mask, etc).  If breathing is difficult, oxygen should be administered by qualified personnel.  Call a physician or transport to a medical facility.  
Ingestion: Do not induce vomiting. Call a physician and/or transport to emergency facility immediately.  
Notes to Physician: Maintain adequate ventilation and oxygenation of the patient.  Chemical eye burns may require extended irrigation.  Obtain prompt consultation, preferably from an ophthalmologist.  Because rapid absorption may occur through the lungs if aspirated and cause systemic effects, the decision of whether to induce vomiting or not should be made by a physician.  If lavage is performed, suggest endotracheal and/or esophageal control.  Danger from lung aspiration must be weighed against toxicity when considering emptying the stomach.  No specific antidote.  Treatment of exposure should be directed at the control of symptoms and the clinical condition of the patient.  
Medical Conditions Aggravated by Exposure: Skin contact may aggravate preexisting dermatitis.  

5.	Fire Fighting Measures

Extinguishing Media: Water fog or fine spray.  Dry chemical fire extinguishers.  Carbon dioxide fire extinguishers.  Foam.  Do not use direct water stream.  Straight or direct water streams may not be effective to extinguish fire.  Alcohol resistant foams (ATC type) are preferred. General purpose synthetic foams (including AFFF) or protein foams may function, but will be less effective.  
Fire Fighting Procedures: Keep people away.  Isolate fire and deny unnecessary entry.  Stay upwind.  Keep out of low areas where gases (fumes) can accumulate.  Water may not be effective in extinguishing fire.  Use water spray to cool fire exposed containers and fire affected zone until fire is out and danger of reignition has passed.  Burning liquids may be extinguished by dilution with water.  Do not use direct water stream.  May spread fire.  Eliminate ignition sources.  Move container from fire area if this is possible without hazard.  Burning liquids may be moved by flushing with water to protect personnel and minimize property damage.  Use caution and test if material is burning before entering area. Material burns with invisible flame.  
Special Protective Equipment for Firefighters: Wear positive-pressure self-contained breathing apparatus (SCBA) and protective fire fighting clothing (includes fire fighting helmet, coat, trousers, boots, and gloves).  If protective equipment is not available or not used, fight fire from a protected location or safe distance.  
Unusual Fire and Explosion Hazards: Container may vent and/or rupture due to fire.  When product is stored in closed containers, a flammable atmosphere can develop.  Electrically ground and bond all equipment.  Flammable mixtures of this product are readily ignited even by static discharge.  Vapors are heavier than air and may travel a long distance and accumulate in low lying areas. Ignition and/or flash back may occur.  Flammable mixtures may exist within the vapor space of containers at room temperature.  Flammable concentrations of vapor can accumulate at temperatures above flash point; see Section 9.  
Hazardous Combustion Products: During a fire, smoke may contain the original material in addition to combustion products of varying composition which may be toxic and/or irritating.  Combustion products may include and are not limited to:  Carbon monoxide.  Carbon dioxide.  
6.	Accidental Release Measures
Steps to be Taken if Material is Released or Spilled: Contain spilled material if possible.  Collect in suitable and properly labeled containers.  Large spills:  Pump with explosion-proof equipment.  If available, use foam to smother or suppress.  Pump into suitable and properly labeled containers.  Ground and bond all containers and handling equipment.  See Section 13, Disposal Considerations, for additional information.    
Ignition Sources Removal:     Eliminate all sources of ignition in vicinity of spill or released vapor to avoid fire or explosion.  Ground and bond all containers and handling equipment.  
Dust Control:   Not applicable.  
Personal Precautions: Use appropriate safety equipment. For additional information, refer to Section 8, Exposure Controls and Personal Protection.  Isolate area.  Refer to Section 7, Handling, for additional precautionary measures.  Keep upwind of spill.  Ventilate area of leak or spill.  No smoking in area.  Eliminate all sources of ignition in vicinity of spill or released vapor to avoid fire or explosion.  Vapor explosion hazard.  Keep out of sewers.  Check area with combustible gas detector before reentering area. Ground and bond all containers and handling equipment.  
Environmental Precautions: Prevent from entering into soil, ditches, sewers, waterways and/or groundwater. See Section 12, Ecological Information.  

7.	Handling and Storage

Handling 
General Handling: Do not swallow.  Avoid contact with eyes, skin, and clothing.  Wash thoroughly after handling.  Avoid breathing vapor.  Keep container closed.  Use with adequate ventilation.  No smoking, open flames or sources of ignition in handling and storage area.  Electrically bond and ground all containers, personnel and equipment before transfer or use of material.  Use of non-sparking or explosion-proof equipment may be necessary, depending upon the type of operation.  
Other Precautions: Containers, even those that have been emptied, can contain vapors. Do not cut, drill, grind, weld, or perform similar operations on or near empty containers.  Never use air pressure for transferring product.  Vapors are heavier than air and may travel a long distance and accumulate in low lying areas. Ignition and/or flash back may occur.  

Storage 
Store in tightly closed, properly vented containers.  Minimize sources of ignition, such as static build-up, heat, spark or flame.  Shelf life:  Use within  
Bulk 	 	 	
12 Months			
Steel drums. 	 	 	
24 Months			

8.	Exposure Controls / Personal Protection
Exposure Limits
Component 	List	Type 	Value 	
| Propan-1-ol; n-propanol	Ireland OELV	TWA  	500 mg/m3  200 ppm   SKIN  	
	Ireland OELV	STEL  	625 mg/m3  250 ppm   SKIN  	
	ACGIH	TWA  	246 mg/m3  100 ppm     	
	UK WEL	TWA  	500 mg/m3  200 ppm   SKIN  	
	UK WEL	STEL  	625 mg/m3  250 ppm   SKIN  	
	ACGIH	TWA  	100 ppm     	

A "skin" notation following the exposure guideline refers to the potential for dermal absorption of the material including mucous membranes and the eyes either by contact with vapors or by direct skin contact.
It is intended to alert the reader that inhalation may not be the only route of exposure and that measures to minimize dermal exposures should be considered.

Personal Protection
Eye/Face Protection: Use chemical goggles.  Chemical goggles should be consistent with EN 166 or equivalent.  Eye wash fountain should be located in immediate work area.  If exposure causes eye discomfort, use a full-face respirator.  
Skin Protection: Use protective clothing chemically resistant to this material.  Selection of specific items such as face shield, boots, apron, or full body suit will depend on the task.  Remove contaminated clothing immediately, wash skin area with soap and water, and launder clothing before reuse or dispose of properly.  
Hand protection: Use chemical resistant gloves classified under Standard EN374: Protective gloves against chemicals and micro-organisms.  Examples of preferred glove barrier materials include:  Natural rubber ("latex").  Neoprene.  Nitrile/butadiene rubber ("nitrile" or "NBR").  Polyethylene.  Ethyl vinyl alcohol laminate ("EVAL").  Polyvinyl chloride ("PVC" or "vinyl").  Viton.  Avoid gloves made of:  Polyvinyl alcohol ("PVA").  When prolonged or frequently repeated contact may occur, a glove with a protection class of 3 or higher (breakthrough time greater than 60 minutes according to EN 374) is recommended.  NOTICE: The selection of a specific glove for a particular application and duration of use in a workplace should also take into account all relevant workplace factors such as, but not limited to: Other chemicals which may be handled, physical requirements (cut/puncture protection, dexterity, thermal protection), potential body reactions to glove materials, as well as the instructions/specifications provided by the glove supplier.  
Respiratory Protection: Respiratory protection should be worn when there is a potential to exceed the exposure limit requirements or guidelines.  If there are no applicable exposure limit requirements or guidelines, use an approved respirator.  Selection of air-purifying or positive-pressure supplied-air will depend on the specific operation and the potential airborne concentration of the material.  For emergency conditions, use an approved positive-pressure self-contained breathing apparatus.  Use the following CE approved air-purifying respirator:  Organic vapor cartridge, type A (boiling point >65 ºC)  
Ingestion: Avoid ingestion of even very small amounts; do not consume or store food or tobacco in the work area; wash hands and face before smoking or eating.  

Engineering Controls
Ventilation: Use engineering controls to maintain airborne level below exposure limit requirements or guidelines.  If there are no applicable exposure limit requirements or guidelines, use only with adequate ventilation.  Local exhaust ventilation may be necessary for some operations.  
9.	Physical and Chemical Properties

Physical StateLiquid	
Color	Colorless	
Odor	Mild	
Flash Point - Closed Cup	25 °C Tag Closed Cup ASTM D56 	
Flash Point - Open Cup	27 °C Tag Open Cup ASTM D1310 	
Flammable Limits In Air	Lower: 2.1 %(V) Literature    	
Upper: 13.7 %(V) Literature    
Autoignition Temperature370.85 °C Literature  	
Vapor Pressure2.0 kPa @ 20 °C Literature 	
Boiling Point (760 mmHg)97.2 °C Literature .   	
Vapor Density (air = 1)2.1 Literature 	
Specific Gravity (H2O = 1)0.806  20 °C/20 °C Literature 	
Freezing Point-126 °C Literature 	
Melting PointNo test data available	
Solubility in Water (by weight)100 % @ 20 °C Literature  pHNo test data available
Molecular Weight60.10 g/mol 	Octanol/Water Partition Coefficient0.25 Measured 	
Evaporation Rate (Butyl Acetate = 1)1.3 	
Kinematic Viscosity	No test data available	
Saturated Vapor Concentration 	No test data available	

10.	Stability and Reactivity

Stability/Instability
Stable.  
Conditions to Avoid: Exposure to elevated temperatures can cause product to decompose.  Avoid static discharge.  

Incompatible Materials: Avoid contact with:  Aldehydes.  Halides.  Halogenated organics.  Halogens.  Strong acids.  Strong oxidizers.  

Hazardous Polymerization
Will not occur.  

Thermal Decomposition
Decomposition products depend upon temperature, air supply and the presence of other materials.  Decomposition products can include and are not limited to:  Carbon monoxide.  Carbon dioxide.  

11.	Toxicological Information
Acute Toxicity
Ingestion
Low toxicity if swallowed.  Small amounts swallowed incidentally as a result of normal handling operations are not likely to cause injury; however, swallowing larger amounts may cause injury.  Aspiration into the lungs may occur during ingestion or vomiting, causing lung damage or even death due to chemical pneumonia.  
LD50, Rat  > 1,870 mg/kg
Eye Contact
May cause severe irritation with corneal injury which may result in permanent impairment of vision, even blindness. Chemical burns may occur.  Vapor may cause eye irritation experienced as mild discomfort and redness.  
Skin Contact
Prolonged exposure not likely to cause significant skin irritation.  May cause drying and flaking of the skin.  May cause more severe response on covered skin (under clothing, gloves).  
Skin Absorption
Prolonged skin contact is unlikely to result in absorption of harmful amounts.  
LD50, Rabbit  4,000 - 10,000 mg/kg
Inhalation
Prolonged excessive exposure may cause adverse effects.  May cause respiratory irritation and central nervous system depression.  Symptoms may include headache, dizziness and drowsiness, progressing to incoordination and unconsciousness.  
LC50, 1 h, Rat  > 39.1 mg/l
Repeated Dose Toxicity
In animals, effects have been reported on the following organs:  Central nervous system.  Liver.  Blood.    
Chronic Toxicity and Carcinogenicity 
Available data are inadequate to evaluate carcinogenicity.  Did not cause cancer in animal skin painting studies.  
Developmental Toxicity
At extremely high concentrations, n-propanol has been reported to cause birth defects in rats. At progressively lower concentrations there were no birth defects.  
Reproductive Toxicity
In animal studies, has been shown to interfere with fertility in males.    
Genetic Toxicology 
In vitro genetic toxicity studies were negative in some cases and positive in other cases.    

12.	Ecological Information
Chemical Fate

Movement & Partitioning
Bioconcentration potential is low (BCF less than 100 or log Pow less than 3).  Potential for mobility in soil is very high (Koc between 0 and 50).  
Henry's Law Constant (H): 7.41E-6 atm*m3/mole; 25 °C  Measured
Partition coefficient, n-octanol/water (log Pow): 0.25  Measured
Partition coefficient, soil organic carbon/water (Koc): 3  Estimated
Distribution in Environment: Mackay Level 1 Fugacity Model: 
Air	Water.	Biota	Soil	Sediment	24.1 %	75.9 %				
Persistence and Degradability
Material is readily biodegradable.  Passes OECD test(s) for ready biodegradability.  
Indirect Photodegradation with OH Radicals
Rate Constant	Atmospheric Half-life	Method	5.48E-12 cm3/s	23 h	Estimated	OECD Biodegradation Tests:  
Biodegradation	Exposure Time	Method	83 %	5 d	OECD 301D Test	83 - 92 %	28 d	OECD 301F Test	Theoretical Oxygen Demand: 2.40 mg/mg
Ecotoxicity 
Material is not classified as dangerous to aquatic organisms (LC50/EC50/IC50 greater than 100 mg/L in most sensitive species).  

Fish Acute & Prolonged Toxicity
LC50, fathead minnow (Pimephales promelas), flow-through, 96 h: 4,480 - 4,630 mg/l
Aquatic Invertebrate Acute Toxicity
EC50, water flea Daphnia magna, 48 h, immobilization: 3,642 mg/l
Toxicity to Micro-organisms
IC50; bacteria, Growth inhibition, 16 h: > 10,000 mg/l
13.	Disposal Considerations

This product, when being disposed of in its unused and uncontaminated state should be treated as a hazardous waste according to EC Directive 91/689/EEC.  Any disposal practices must be in compliance with all national and provincial laws and any municipal or local by-laws governing hazardous waste.  For used, contaminated and residual materials additional evaluations may be required.  Do not dump into any sewers, on the ground, or into any body of water.  

14.	Transport Information
Road & Rail 
Proper Shipping Name: N-PROPANOL
Hazard Class: 3   ID Number: UN1274   Packing Group: PG III

Classification: F1
Kemler Code: 30
Tremcard Number: 30GF1-III
Ocean
Proper Shipping Name: N-PROPANOL
Hazard Class: 3   ID Number: UN1274   Packing Group: PG III
EMS Number: F-E,S-D 
Marine pollutant.: No

Air
Proper Shipping Name: N-PROPANOL
Hazard Class: 3   ID Number: UN1274   Packing Group: PG III
Cargo Packing Instruction: 310
Passenger Packing Instruction: 309

Inland Waterways
Proper Shipping Name: N-PROPANOL
Hazard Class: 3   ID Number: UN1274   Packing Group: PG III
Classification: F1
Kemler Code: 30
Tremcard Number: 30GF1-III

15.	Regulatory Information

European Inventory of Existing Commercial Chemical Substances (EINECS)
The components of this product are on the EINECS inventory or are exempt from inventory requirements.
US. Toxic Substances Control Act
All components of this product are on the TSCA Inventory or are exempt from TSCA Inventory requirements under 40 CFR 720.30

EC Classification and User Label Information
Hazard Symbol :
F	-	Highly flammable.	
Xi	-	Irritant.	
Risk Phrases :
R11 - Highly flammable.
R41 - Risk of serious damage to eyes.
R67 - Vapours may cause drowsiness and dizziness.

Safety Phrases :
S16 - Keep away from sources of ignition - no smoking.
S24 - Avoid contact with skin.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39 - Wear eye/face protection.
Chemical NamePropan-1-ol; n-propanol
(EC Label)   (EC # 200-746-9 )

16.	Other Information
Risk-phrases in the Composition section
R11	Highly flammable.	

Revision 
Identification Number: 1544 / 3005 / Issue Date 2007/07/11 / Version: 3.0
Most recent revision(s) are noted by the bold, double bars in left-hand margin throughout this document. 

Dow Chemical Company Ltd  urges each customer or recipient of this (M)SDS to study it carefully and consult appropriate expertise, as necessary or appropriate, to become aware of and understand the data contained in this (M)SDS and any hazards associated with the product.  The information herein is provided in good faith and believed to be accurate as of the effective date shown above.  However, no warranty, express or implied, is given.   Regulatory requirements are subject to change and may differ between various locations. It is the buyer's/user's responsibility to ensure that his activities comply with all federal, state, provincial or local laws.  The information presented here pertains only to the product as shipped.  Since conditions for use of the product are not under the control of the manufacturer, it is the buyer's/user's duty to determine the conditions necessary for the safe use of this product.   Due to the proliferation of sources for information such as manufacturer-specific (M)SDSs, we are not and cannot be responsible for (M)SDSs obtained from any source other than ourselves.  If you have obtained an (M)SDS from another source or if you are not sure that the (M)SDS you have is current, please contact us for the most current version.